What is Cushing Syndrome: Understanding causes, symptoms, risk factors, and how to live with high cortisol |

Cushing Syndrome is a relatively uncommon hormonal disorder that arises as a consequence of chronically elevated levels of cortisol in the body. Cortisol serves to play a vital role in controlling blood pressure, the metabolic rate, blood sugar levels, and the “stress response system.” Nonetheless, as a result of chronically elevated levels of this critical hormone within the body, a range of complications may arise. The two causes that bring about Cushing’s Syndrome are the result of taking steroid pills over a period of time, as well as an overproduction of these hormones by an individual’s body, which could often be a consequence of a “tumour.” Despite its complications, it has been noted that “there are treatments available that work well if caught early.

Understanding crushing syndrome and its forms

Cushing syndrome, also known as hypercortisolism, is a group of symptoms caused by exposure to excessive cortisol levels for a prolonged period of time. Cortisol is produced by the adrenal glands, which are controlled by instructions sent from the pituitary gland and the hypothalamus, which is situated in the brain. All of these work in conjunction to ensure that there is a proper balance of hormones. Any disruption to this function can lead to an overproduction of cortisol.There are two forms of Cushing Syndrome. In the case of endogenous Cushing syndrome, the body produces an excess amount of cortisol on its own. On the other hand, exogenous Cushing syndrome is the result of external sources like the long-term administration of corticosteroids like prednisone.

Who is most affected by the Crushing Syndrome effect

It can occur in people of all ages, including children, although the most affected age range is between 25 and 50 years. It tends to affect women more than men. People who have used steroid medication, especially those with conditions like asthma, rheumatoid arthritis, and those who have conditions resulting from autoimmune diseases, are at a greater risk of developing the condition.Though it has gained considerable attention, it remains an uncommon condition, estimated to occur in 40 to 70 cases per million population yearly.

Causes of high cortisol output

There are several underlying causes of high cortisol output. The main cause of high cortisol secretion in the body is the use of glucocorticoids as a medication for managing inflammation. Normally, glucocorticoids can affect the body’s physiological negative feedback.Other causes include the presence of pituitary gland tumours that secrete excess amounts of ACTH or the presence of tumours within the adrenal gland that secrete cortisol. Additionally, other non-adrenal tissues within the body that secrete ACTH may be attributed to the development of this condition because they are ectopic tissues and mostly found within the lungs and are malignant.In the vast majority of cases, the condition is not inherited but appears spontaneously.

Common symptoms of Crushing Syndrome (high coristol)

Can Cushing Syndrome be prevented

There is no way to prevent Cushing syndrome, especially if it is caused by tumours. People taking steroid treatments should be closely watched by a doctor, especially if they take them for a long period. The lowest dose should also be taken for a shorter period of time to prevent it.

Living with Cushing Syndrome

Suffering from Cushing syndrome can sometimes have physical as well as psychological aspects. In this case, physical changes and physical conditions of fatigue may influence confidence and mental health. Healthcare professionals and mental health practitioners play a significant role in this regard. If the condition is diagnosed early, individuals with Cushing syndrome can be treated, and their health should improve. Many people with Cushing syndrome get their health back.